The Health and Safety Executive's 2024/25 statistics reveal a mixed picture for work-related MSDs. Whilst total cases decreased to 511,000 workers, new cases rose to 173,000 and upper limb injuries increased to 41%. With 7.1 million working days lost, this analysis examines what these trends mean for businesses across Northern Ireland, the UK and Ireland in high-risk sectors and why proactive Ergonomic intervention remains critical.